
Professor In Residence
Lab Role
+1 415 221-4810 ext. 23650
short description of what you do
Publications
Overview of ADNI MRI.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Personalizing progressive changes to brain structure in Alzheimer's disease using normative modeling.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Standardized statistical framework for comparison of biomarkers: Techniques from ADNI.
Alzheimer's & dementia : the journal of the Alzheimer's Association
A worldwide study of white matter microstructural alterations in people living with Parkinson's disease.
NPJ Parkinson's disease
Design and validation of the ADNI MR protocol.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning.
Brain imaging and behavior
Association of CSF α-Synuclein Seed Amplification Assay Positivity with Disease Progression and Cognitive Decline: A Longitudinal Alzheimer's Disease Neuroimaging Initiative Study.
medRxiv : the preprint server for health sciences
Head-to-head comparison of leading blood tests for Alzheimer's disease pathology.
medRxiv : the preprint server for health sciences
Sex, racial, and APOE-ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
bioRxiv : the preprint server for biology
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic and Clinical Correlates of AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals.
JAMA psychiatry
Automated Quality Evaluation Index for Arterial Spin Labeling Derived Cerebral Blood Flow Maps.
Journal of magnetic resonance imaging : JMRI
Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability.
International psychogeriatrics
Individuals with Alzheimer's disease and low tau burden: Characteristics and implications.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo.
Nature. Mental health
Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
medRxiv : the preprint server for health sciences
Genomic loci influence patterns of structural covariance in the human brain.
Proceedings of the National Academy of Sciences of the United States of America
Relationship of Hoarding and Depression Symptoms in Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Hoarding Symptoms in Late Life Depression are Associated With Greater Executive Dysfunction and Disability and Poorer Response to Depression Treatment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group.
Pain medicine (Malden, Mass.)
A universal neocortical mask for Centiloid quantification.
Alzheimer's & dementia (Amsterdam, Netherlands)
Personalising Alzheimer's Disease progression using brain atrophy markers.
medRxiv : the preprint server for health sciences
Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4.
Alzheimer's & dementia : the journal of the Alzheimer's Association
A 1-year randomized controlled trial of a nutritional blend to improve nutritional biomarkers and prevent cognitive decline among community-dwelling older adults: The Nolan Study.
Alzheimer's & dementia (New York, N. Y.)
Cognitive outcomes are differentially associated with depression severity trajectories during psychotherapy treatment for late life major depressive disorder.
International journal of geriatric psychiatry
β-amyloid PET harmonisation across longitudinal studies: Application to AIBL, ADNI and OASIS3.
NeuroImage
Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer's disease pathology measured with biomarkers.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
JAMA psychiatry
Network-wise concordance of multimodal neuroimaging features across the Alzheimer's disease continuum.
Alzheimer's & dementia (Amsterdam, Netherlands)
Multiple Cortical to Striatal Accumulation Trajectories of β-Amyloid: Do All Roads Lead to Rome?
Neurology
Regional uptakes from early-frame amyloid PET and 18F-FDG PET scans are comparable independent of disease state.
European journal of hybrid imaging
Age-dependent brain morphometry in Major Depressive disorder.
NeuroImage. Clinical
Thalamic Dorsomedial Nucleus Free Water Correlates with Cognitive Decline in Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society
Using imputation to provide harmonized longitudinal measures of cognition across AIBL and ADNI.
Scientific reports
White matter changes in drug-naïve Parkinson's disease patients with impulse control & probable REM sleep behavior disorders.
Journal of the neurological sciences
Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Network-constrained technique to characterize pathology progression rate in Alzheimer's disease.
Brain communications
The search for a convenient procedure to detect one of the earliest signs of Alzheimer's disease: A systematic review of the prediction of brain amyloid status.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Lower cerebral perfusion is associated with tau-PET in the entorhinal cortex across the Alzheimer's continuum.
Neurobiology of aging
Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers.
Brain communications
The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression.
Journal of Alzheimer's disease : JAD
Improvements in Functional Disability After Psychotherapy for Depression Are Associated With Reduced Suicide Ideation Among Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project.
Biological psychiatry
Impact of hybrid supervision approaches on the performance of artificial intelligence for the classification of chest radiographs.
Computers in biology and medicine
Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study.
Movement disorders : official journal of the Movement Disorder Society
Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study.
The Lancet. Neurology
Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.
Brain : a journal of neurology
Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.
Neurobiology of aging
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Brain : a journal of neurology
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort.
Annals of clinical and translational neurology
Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment.
International journal of geriatric psychiatry
Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.
Neurobiology of aging
Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort.
Movement disorders : official journal of the Movement Disorder Society
Preserved Structural Network Organization Mediates Pathology Spread in Alzheimer's Disease Spectrum Despite Loss of White Matter Tract Integrity.
Journal of Alzheimer's disease : JAD
Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
NeuroImage. Clinical
Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary Report.
Alzheimer's & dementia (New York, N. Y.)
Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals.
Brain : a journal of neurology
Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Independent value added by diffusion MRI for prediction of cognitive function in older adults.
NeuroImage. Clinical
Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD.
Annals of clinical and translational neurology
Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults.
Neurobiology of aging
Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimer's disease clinical trial cohort.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology.
Neurology
Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder.
Frontiers in behavioral neuroscience
Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly.
Frontiers in aging neuroscience
Discriminative Power of Arterial Spin Labeling Magnetic Resonance Imaging and 18F-Fluorodeoxyglucose Positron Emission Tomography Changes for Amyloid-β-Positive Subjects in the Alzheimer's Disease Continuum.
Neuro-degenerative diseases
Cortical thickness and sulcal depth: insights on development and psychopathology in paediatric epilepsy.
BJPsych open
Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.
Annals of clinical and translational neurology
Brain amyloid-β burden is associated with disruption of intrinsic functional connectivity within the medial temporal lobe in cognitively normal elderly.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
NeuroImage. Clinical
Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment.
Brain : a journal of neurology
Multimodal MRI-based Imputation of the Aβ+ in Early Mild Cognitive Impairment.
Annals of clinical and translational neurology
Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults.
Neurobiology of aging
Neuroimaging predictors of brain amyloidosis in mild cognitive impairment.
Annals of neurology
CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders.
Translational psychiatry
Voxel-wise co-analysis of macro- and microstructural brain alteration in mild cognitive impairment and Alzheimer's disease using anatomical and diffusion MRI.
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Voxelwise multivariate analysis of multimodality magnetic resonance imaging.
Human brain mapping
Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Patterns of Reduced Cortical Thickness in Late-Life Depression and Relationship to Psychotherapeutic Response.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Increased Cortical Thickness in Male-to-Female Transsexualism.
Journal of behavioral and brain science
Impact of apolipoprotein E4-cerebrospinal fluid β-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Impact of methodologic choice for automatic detection of different aspects of brain atrophy by using temporal lobe epilepsy as a model.
AJNR. American journal of neuroradiology
Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia.
International journal of Alzheimer's disease
Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities.
Human brain mapping
Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment.
Brain : a journal of neurology
Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence.
Alcoholism, clinical and experimental research
Deformation-based morphometry of prospective neurodevelopmental changes in new onset paediatric epilepsy.
Brain : a journal of neurology
Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data.
Journal of Alzheimer's disease : JAD
Nonlinear time course of brain volume loss in cognitively normal and impaired elders.
Neurobiology of aging
Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study.
Neurobiology of aging
Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative.
Alzheimer's & dementia : the journal of the Alzheimer's Association
An integrated multimodality MR brain imaging study: gray matter tissue loss mediates the association between cerebral hypoperfusion and Alzheimer's disease.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
A geometry-driven optical flow warping for spatial normalization of cortical surfaces.
IEEE transactions on medical imaging
3-D analysis of cortical morphometry in differential diagnosis of Parkinson's plus syndromes: mapping frontal lobe cortical atrophy in progressive supranuclear palsy patients.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Cortical reconstruction using implicit surface evolution: accuracy and precision analysis.
NeuroImage
Cortical surface alignment using geometry driven multispectral optical flow.
Information processing in medical imaging : proceedings of the ... conference
Mapping techniques for aligning sulci across multiple brains.
Medical image analysis
Cortical surface segmentation and mapping.
NeuroImage